CHAPTER ONE: THE CELL AS A UNIT OF HEALTH AND DISEASE
CNVs - consist of different numbers of large contiguous stretches of DNA from one thousand base pairs to millions of base pairs
Epigenetics - heritable changes in gene expression that are not caused by alterations in DNA sequence
Micro-RNA and Long Noncoding RNA
Small interfering RNAs (siRNAs) - short RNA sequences that can be introduced into cells
Long Noncoding RNA (lncRNA)
Cell movement is accomplished through the cytoskeleton
Mitochondria - where most ATP are made through oxidative phosphorylation
Organellar biogenesis - replication of organelles
Glycolipids and sphingomyelin
Passive Membrane Diffusion.
Receptor-Mediated and Fluid-Phase Uptake.
Biosynthetic Machinery: Endoplasmic Reticulum and Golgi.
Waste Disposal: Lysosomes and Proteasomes.
Cellular Metabolism and Mitochondrial Function.
SIGNAL TRANSDUCTION PATHWAYS
G-protein coupled receptors, GPCRs
Other classes of receptors
Modular Signaling Proteins, Hubs, and Nodes
GROWTH FACTORS AND RECEPTORS
INTERACTION WITH THE EXTRACELLULAR MATRIX
Adhesive glycoproteins and adhesion receptors
Proliferation and the Cell Cycle
Tissue stem cells (adult stem cells)