Chapter nineteen Chemical Coordination and Integration

Chapter nineteen Chemical Coordination and Integration

UNIT five

The reductionist approach to study of life forms resulted in increasing use of physico-chemical concepts and techniques. Majority of these studies employed either surviving tissue model or straightaway cell-free systems. An explosion of knowledge resulted in molecular biology. Molecular physiology became almost synonymous with biochemistry and biophysics. However, it is now being increasingly realised that neither a purely organismic approach nor a purely reductionistic molecular approach would reveal the truth about biological processes or living phenomena. Systems biology makes us believe that all living phenomena are emergent properties due to interaction among components of the system under study. Regulatory network of molecules, supra-molecular assemblies, cells, tissues, organisms and indeed, populations and communities, each create emergent properties. In the chapters under this unit, major human physiological processes like, exchange of gases, blood circulation, locomotion and movement are described in cellular and molecular terms. The last two chapters point to the coordination and regulation of body events at the organismic level.

ALFONSO CORTI, Italian anatomist, was born in eighteen twenty-two. Corti began his scientific career studying the cardiovascular systems of reptiles. Later, he turned his attention to the mammalian auditory system. In eighteen fifty-one, he published a paper describing a structure located on the basilar membrane of the cochlea containing hair cells that convert sound vibrations into nerve impulses, the organ of Corti. He died in the year eighteen eighty-eight.

Fourteen point one Respiratory Organs

Fourteen point two Mechanism of Breathing