Corrected: Hemorrhagic Stroke in a Twenty-Four-Year-Old Male With Polycythemia Vera: A Case Report and Literature Review
Corrected: Hemorrhagic Stroke in a Twenty-Four-Year-Old Male With Polycythemia Vera: A Case Report and Literature Review
This article has been corrected to fix a typo in the first sentence of the Discussion section:
· Original: "PV was first described in nineteen eighty-two and has an incidence of two point five to ten per one thousand people."
· Corrected: "PV was first described in nineteen eighty-two and has an incidence of two point five to ten per one million people."
Abstract
Abstract
Stroke is the second leading cause of death worldwide, according to the latest report by the World Health Organization. Intracerebral hemorrhage comprises twenty to twenty-five percent of the stroke in the young, with incidence rates of three to six in one hundred thousand people per year. One of the most common and important causes of hemorrhagic stroke in the general population is hypertension. Polycythemia vera can manifest with both cranial thrombosis and hemorrhage. We report a twenty-four-year-old male, known hypertensive, who presented as a pontine hemorrhage. Further examination with imaging and laboratory tests demonstrated a diagnosis of polycythemia vera. In polycythemia vera, platelet dysfunction and acquired Von Willebrand syndrome are predisposing factors to bleeding. Associated blood viscosity and the proinflammatory state cause vascular remodeling, leading to hypertension. These mechanisms have collectively been described to cause hemorrhagic stroke in polycythemia vera.