Dentinogenic Ghost Cell Tumor (Formerly Calcifying Odontogenic Cyst)- Differential Diagnosis

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ODONTOGENIC TUMORS

CANCER

Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, go beyond their usual boundaries to invade adjoining parts of the body and/or spread to other organs. A neoplasm and malignant tumor are other common names for cancer. WHO

NEOPLASM- Classification

Benign

· Lipoma

· Fibroma

· Hemangioma

· Adenoma

· Pre-Cancerous or Pre-Malignant

ONCOLOGY

ODONTOGENIC TUMORS Epithelial Tumors Mesenchymal Tumors

ODONTOGENIC TUMORS

Malignant

Ameloblastoma- Clinical Features

Ameloblastoma- Radiographic Features

Ameloblastoma- Biological Subtypes

Histopathology

Microscopic Patterns

Treatment

Malignant variants of Ameloblastomas

Ameloblastoma and Ameloblastic Carcinoma

Sinonasal Ameloblastoma

Ameloblastoma- Differential Diagnosis

Ameloblastoma- Treatment and Prognosis

Calcifying Epithelial Odontogenic Tumor (Pindborg Tumor).

Calcifying Epithelial Odontogenic Tumor (Pindborg Tumor)- Clinical Features

Calcifying Epithelial Odontogenic Tumor (Pindborg Tumor)- Histopathology

Calcifying Epithelial Odontogenic Tumor (Pindborg Tumor)-Differential Diagnosis

Calcifying Epithelial Odontogenic Tumor (Pindborg Tumor)- Treatment

Adenomatoid Odontogenic Tumor

Adenomatoid Odontogenic Tumor Radiographic Features

Adenomatoid Odontogenic Tumor Histopathology

Adenomatoid Odontogenic Tumor- Differential Diagnosis

Adenomatoid Odontogenic Tumor- Treatment

Squamous Odontogenic Tumor

Clear Cell Odontogenic Tumor (Carcinoma)

Clear Cell Odontogenic Tumor (Carcinoma)- Differential Diagnosis

Clear Cell Odontogenic Tumor (Carcinoma)

Clinical Features

Histopathology

Microscopic Differential Diagnosis

Behavior

Keratocystic Odontogenic Tumor/ Odontogenic Keratocyst

Keratocystic Odontogenic Tumor/ Odontogenic Keratocyst- Etiology and Pathogenesis

Factors that may contribute to the pathogenesis of the OKC/KCOT:

Keratocystic Odontogenic Tumor/ Odontogenic Keratocyst- Clinical Features

Keratocystic Odontogenic Tumor/ Odontogenic Keratocyst- Histopathology

Keratocystic Odontogenic Tumor/ Odontogenic Keratocyst- Treatment and Prognosis

Dentinogenic Ghost Cell Tumor (Formerly Calcifying Odontogenic Cyst)

Dentinogenic Ghost Cell Tumor (Formerly Calcifying Odontogenic Cyst)- Etiology and Pathogenesis

Dentinogenic Ghost Cell Tumor (Formerly Calcifying Odontogenic Cyst)- Clinical Features

Dentinogenic Ghost Cell Tumor (Formerly Calcifying Odontogenic Cyst)- Radiographic Features

Dentinogenic Ghost Cell Tumor (Formerly Calcifying Odontogenic Cyst)- Histopathology

Dentinogenic Ghost Cell Tumor (Formerly Calcifying Odontogenic Cyst)- Differential Diagnosis

Dentinogenic Ghost Cell Tumor (Formerly Calcifying Odontogenic Cyst)- Treatment and Prognosis

MESENCHYMAL TUMORS

Central Odontogenic Fibroma

Cementoblastoma

Odontogenic Myxoma

Odontogenic Myxoma- Clinical Features

Odontogenic Myxoma- Radiographic Features

Odontogenic Myxoma- Histopathology

Odontogenic Myxoma- Differential Diagnosis

Odontogenic Myxoma- Treatment

· BOX eleven dash twelve Odontogenic Myxoma (Fibromyxoma)

Clinical Features

Histopathology

Microscopic Differential Diagnosis

Behavior

Central Odontogenic Fibroma

Microscopic Differential Diagnosis

Cementoblastoma

Cementoblastoma- Radiographic Features

Cementoblastoma- Histopathology

Cementoblastoma- Differential Diagnosis

Cementoblastoma- Treatment

· BOX eleven dash fourteen Cementoblastoma

Histologic features of osteoblastoma

Periapical Cemento-osseous Dysplasia

Periapical Cemento-osseous Dysplasia- Clinical Features

Periapical Cemento-osseous Dysplasia- Radiographic Features

Florid Cemento-Osseous Dysplasia

Periapical Cemento-osseous Dysplasia- Histopathology

Florid Cemento-Osseous Dysplasia Histopathology and Treatment

Periapical Cemento-osseous Dysplasia Differential Diagnosis

Florid Cemento-Osseous Dysplasia- Differential Diagnosis

Periapical Cemento-osseous Dysplasia- Treatment

MIXED TUMORS

Amelobastic Fibro-odontoma

Ameloblastic Fibroma and Ameloblastic Fibro-odontoma

Ameloblastic Fibroma and Ameloblastic Fibro-odontoma- Clinical Features

Ameloblastic Fibroma and Ameloblastic Fibro-odontoma- Radiographic Features

Ameloblastic Fibroma and Ameloblastic Fibro-odontoma- Histopathology

Ameloblastic Fibroma and Ameloblastic Fibro-odontoma- Differential Diagnosis

Ameloblastic Fibroma and Ameloblastic Fibro-odontoma- Treatment

Ameloblastic Fibrosarcoma

Odontomas

Odontomas- Clinical Features

Odontomas- Radiographic Features

Odontomas- Histopathology

Odontomas- Differential Diagnosis

Odontomas- Treatment

"BENIGN NON- ODONTOGENIC TUMORS"

FIBROUS DYSPLASIA

OSTEOBLASTOMA/ OSTEOID OSTEOMA

DESMOPLASMIC FIBROMA

CENTRAL GIANT CELL GRANULOMA

HEMANGIOMA OF BONE

TORI AND EXOSTOSES

OSSIFYING FIBROMA

· BOX twelve dash three Ossifying Fibroma

Third and fourth decades

Histopathology

Treatment

Clinical Features

Radiographic Features

Juvenile Ossifying Fibroma

Juvenile psammomatoid ossifying fibroma

Juvenile Trabecular Ossifying Fibroma

Juvenile Psammomatoid Ossifying Fibroma

Histopathology

Differential Diagnosis

Osteoblastoma

Treatment and Prognosis

FIBROUS DYSPLASIA

Clinical Features

Histopathology

Treatment

Etiology and Pathogenesis

Clinical Features

McCune-Albright syndrome

Jaffe-Lichtenstein syndrome

Radiographic Features

Histopathology

Differential Diagnosis

Treatment and Prognosis

OSTEOBLASTOMA/ OSTEOID OSTEOMA

Clinical Features

Radiographic Features

Histopathology

Differential Diagnosis

Treatment and Prognosis

OSTEOMA

Periosteal Osteomas- osteomas that arise on the surface of bone

Clinical Features

Histopathology

Differential Diagnosis

Treatment and Prognosis

Desmoplastic fibroma.

Clinical Features

Radiographic Features

Histopathology

Differential Diagnosis

Fibrosarcoma- greater cellularity, mitotic figures, and nuclear pleomorphism.

Treatment of Choice: Surgical resection.

Chondroma.

Central giant cell granuloma.

Clinical Features

Histopathology

Treatment

Etiology and Pathogenesis

Clinical Features

Radiographic Features

Histopathology

Differential Diagnosis

Hyperparathyroidism.

Cherubism.

Hyperparathyroidism.

Aneurysmal Bone Cyst.

Cherubism.

Treatment and Prognosis

Giant cell tumor.

Treatment: Surgical Excision.

Clinical Features

Radiographic Features

Histopathology

Differential Diagnosis

Treatment and Prognosis

LANGERHANS CELL DISEASE

Etiology and Pathogenesis

Clinical Features

Oral changes: initial presentation in all forms of this disorder

Radiographic Features

Histopathology

Differential Diagnosis

Treatment and Prognosis

Localized Disease

Disseminated Disease

TORI AND EXOSTOSES

Etiology and Pathogenesis

Clinical Features

Bony exophytic growths that appear along the lingual aspect of the mandible superior to the mylohyoid ridge

EXOSTOSES

Treatment and Prognosis

CORONOID HYPERPLASIA

Clinical Features

Radiographic Features

Histopathology

Differential Diagnosis

Treatment and Prognosis

Overview

The document provides an extensive overview of the Dentinogenic Ghost Cell Tumor, detailing its characteristics, potential for recurrence, and differential diagnoses. It aims to inform medical professionals about the tumor's behavior and management strategies.

Key Points

1Dentinogenic Ghost Cell Tumor is a developmental odontogenic lesion with potential for recurrence
2It shows aggressive clinical behavior compared to simpler lesions
3The tumor typically occurs in the maxilla, especially among females
4Characteristic features include ghost cell keratinization and well-demarcated radiolucencies
5Treatment is generally more aggressive than simple curettage.

Details

Authors: Dr PATRICIA DYAN L. LIGON
Category: Health and Medicine

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